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Stay on Your Side of the Line

Stephen Quake is back doing a guest post at Olivia Judson's blog, this time focusing on the "artificial divisions" between pure and applied research. Over the years, he says, there have been many examples of researchers, from Archimedes and Lord Kelvin no less, who made both fundamental scientific discoveries and applied ones. "The stereotyped view is that the applied scientists control the lion’s share of funding, while the basic scientists control the most prestigious journals and prizes. The reality is more complicated and lies somewhere in between," Quake writes.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.