The State of It

It's been a little more than 15 years since the kickoff of public health genomics, writes Muin Khoury, the director of the Centers for Disease Control and Prevention's Office of Public Health Genomics, at the Genomics and Health Impact Blog. With technological improvements in whole-genome sequencing, it is increasingly being applied to detect and control infectious disease outbreaks as well as to determine which people are at increased risk of developing rare and common diseases.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.