At Freelancing Science, blogger Pawe³ Szczêsny offers a quick rundown of some online tools that can be used in protein sequence annotation with examples he got from using the same sequence on each site. His focus is not on performance, but rather on the differences between the visualization methods offered by each tool. On his list: SMART, PFAM, CDD, and HHpred. Szczêsny notes that he "may have something to add pretty soon" to the group of tools.