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On Stage and in Song

As part of his 2012 TedMed talk, the US National Institutes of Health Director Francis Collins says that the time between understanding the molecular cause of a disease and developing a drug to treat that disease is too long, and the process is too expensive. Collins further suggests that drugs that have been shown to be safe in humans — though not effective for their original target diseases — could be repurposed for other diseases, as the new National Center for Advancing Translational Sciences is aiming to do.

Collins also joined singer Jill Sobule on the stage.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.