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The Sound of a Giant Approaching Would Scare Us, Too

Derek Lowe talks job news at his blog, In the Pipeline. Apparently a potential Roche takeover has spurred a lot of Genentech employees to start looking elsewhere. "Some other Bay area biotechs are apparently seeing shoals of CVs coming in," he says. If you're looking on the east coast, though, good news is that Merck, EMD-Serono, and the NIH Chemical Genomics Center are all hiring.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.