Having their genome in hand may not help people prevent or treat disease, says The Boston Globe. Further, even knowing how genes interact with each other and how genes interact with the environment may not help very much. A new study in The American Journal of Human Genetics from Harvard School of Public Health's Peter Kraft and his colleagues found that "the inclusion of G-G and G-E interaction effects in risk-prediction models is unlikely to dramatically improve the discrimination ability of these models." The study's lead author Hugues Aschard tells the Globe that the utility of genetic mutations associated with disease is still uncertain.
May 25, 2012