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Solved!

What has taken researchers more than a decade to chip away it, gamers solved in weeks "from the comfort of their own homes," The Scientist says. Foldit players have solved the structure of a retroviral protease of the Mason-Pfizer monkey virus; their solution and its validation appear in a paper published online in advance in Nature Structural & Molecular Biology this week. The University of Washington's David Baker, the Foldit creator, tells Nature's News blog that "the M-PMV structure had stumped scientists for a very long time before Foldit players made their breakthrough, adding: "This is the first example I know of game players solving a long-standing scientific problem."

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.