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SOLiD Saga

At PolITiGenomics, David Dooling points out a letter that the senior director of scientific operations at ABI, Kevin McKernan, wrote to the UK House of Lords last November. In it, he says that the Sanger Centre is biased against ABI due to the company's association with Craig Venter during the human genome sequencing race and says the center had close ties to Solexa. The Sanger Centre returned five SOLiD instruments and instead purchased more Illumina Genome Analyzers — McKernan's letter included a news story from our sister publication GenomeWeb Daily News on the return of the instruments. "It doesn't seem right to impugn someone else's character in that way when there are countless other reasons -- scientific reasons -- why the Sanger Institute would make that choice," Dooling says to Nature's The Great Beyond blog.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.