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So Simple, But so Easy to Mess Up

There are many different ways to mess up an experiment, and Emily Crow at Bitesize Bio gives five ways "to destroy your agarose gel." Her favorite ways to do so include using water instead of TAE or TBE buffer, not adding the ethidium bromide, and just dropping the nicely made gel on the floor, among others. "Pouring and running an agarose gel is a simple and routine procedure that you probably learned soon after joining your first lab. A procedure that couldn't possibly go wrong," Crow says."Or so you'd think. In fact, there are a surprising number of ways to destroy your agarose gel."