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So Much For Eating Right

By studying centenarians, their children, and controls, researchers led by Yousin Suh have found a potential role for insulin growth factor one in human longevity. The scientists screened IGF1 and the IGF1 receptor genes in their study population and found a gender-specific effect. Female centenarians, as they report in PNAS, are more likely to have a heterozygous mutation in the IGF1 receptor gene that results in an altered IGF signaling pathway.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.