Logo

So More Complicated Than Using a Food Processor?

May 19, 2009

The Scientist chats with Elaine Mardis, George Church, Andy Gnirke, Hanlee Ji, and Jonathan and Christine Seidman about their preferred methods to fractionate DNA bound for exon sequencing or genome partitioning in next-gen sequencers. Church uses padlock probes while the Seidmans prefer surface capture-based hybridization. "Being able to design a genome-unique set of capture probes or PCR products is not always as easy as it sounds," Mardis adds.

Breaking News
The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.