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So Long, Princeton (and All Those Others)

Now that Pfizer's acquisition of Wyeth is complete, the cuts are coming -- this week, the pharma announced that it would shut down six of its 20 research facilities (with some question marks hanging over others). "Pfizer didn't say how many R&D jobs it would cut or how much it hoped to save from the shutdowns," according to this news analysis story from the Wall Street Journal.

Among the sites being closed: Princeton, NJ; Chazy, Rouses Point, and Plattsburgh, NY; Gosport, Slough, and Taplow in the UK; and Sanford and Research Triangle Park, NC. WSJ adds that Pfizer "is also planning to move work from its Collegeville, Pa.; Pearl River, N.Y., and St. Louis sites to other locations."

The Associated Press has a helpful list of the closed and remaining sites, as well as what scientific activities are centered at each. And if you really want to delve into this, Pharmaconduct has put together a spreadsheet listing Pfizer's facilities going back through several of its last acquisitions and detailing the status of each.

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.