Skip to main content
Premium Trial:

Request an Annual Quote

Smaller Potential of the Personal

Personalized medicine of the "the right drug for the right patient at the right time" ethos may help patients, but Forbes' Henry Miller writes that it might not be right for drug companies.

"[W]hen drugs are ultimately approved based on the use of biomarkers, the description of the medication’s approved uses on the label might be narrower, or more restrictive, thereby reducing the size of the patient population for whom the drug is intended — and the revenue potential," he says.

Additionally, Miller writes that regulatory burden may become difficult to shoulder, as drugmakers will need more focused clinical trials to show efficacy and larger studies to prove safety.

That in combination with the time and resources needed to uncover biomarkers and develop them into a diagnostic test or clinical algorithm to accompany the drug "could impose huge development costs that might never be recovered by the manufacturers."

The Scan

Genetic Ancestry of South America's Indigenous Mapuche Traced

Researchers in Current Biology analyzed genome-wide data from more than five dozen Mapuche individuals to better understand their genetic history.

Study Finds Variants Linked to Diverticular Disease, Presents Polygenic Score

A new study in Cell Genomics reports on more than 150 genetic variants associated with risk of diverticular disease.

Mild, Severe Psoriasis Marked by Different Molecular Features, Spatial Transcriptomic Analysis Finds

A spatial transcriptomics paper in Science Immunology finds differences in cell and signaling pathway activity between mild and severe psoriasis.

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.