Skip to main content
Premium Trial:

Request an Annual Quote

Into Smaller Pieces

A panel has advised the National Institute of General Medical Sciences to end its Large-Scale Collaborative Project Awards Program, also known as glue grants, reports ScienceInsider. The program began in 2000 as a way for NIGMS to fund large-scale biology projects involving multiple researchers at different institutes. The outcome assessment report is based on a community survey, a literature analysis, and Web site usage analysis, ScienceInsider notes, and it found that two of the five original grants were successes and one had "significant flaws." According to ScienceInsider, “the report points to inadequate oversight by NIGMS, goals set by the groups that were ‘inflexible’ or ‘too sweeping or too narrow,’ ‘missing expertise,’ and poor outreach to the rest of the scientific community.” The panel, however, does not say that NIGMS should stay away from large science, but rather that it should fund it through more, but smaller, awards.

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.