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Small Company, Big Drug

Will biotech “castoffs” develop the next blockbuster drugs?, asks a recent Wall Street Journal article ($). The article profiles Speedel Holding AG, and its founder Alice Huxley, who successfully created and developed drug aliskiren as a potential blockbuster—in the privacy of her own home.  Big pharma are casting off slow-to-move projects, and small startups, such as Huxley’s own company, are finding opportunities in the rejects.


 

The Scan

Rise of BA.5

The New York Times reports that the Omicron subvariant BA.5 has become the dominant version of SARS-CoV-2 in the US.

UK Health Secretary Resigns

Sajid Javid, the UK health secretary, resigned along with Chancellor Rishi Sunak, saying they cannot work with Prime Minister Boris Johnson's government, CNN reports.

Clones From Freeze-Dried Cells

A team in Japan has cloned mice from freeze-dried skin cells, according to the Guardian.

Genome Research Papers on Craniosynostosis, Macaque Retrotransposition, More

In Genome Research this week: structural variants in craniosynostosis, LINE-1 activity in rhesus macaque brain, and more.