The Slow Transition

Washington University in St. Louis' Dan Koboldt blogs about their transition from a capillary-based to a massively parallel sequencing platform. They formed a focus group to look at the different programs for aligning and detecting variants in next-gen sequence data and have decided to test five or six of them with data from the work they've done on the 1000 Genomes Project. Those aligners being tested include Maq, Eland, BLAT, and cross_match.

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.