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The University of Illinois' Huimin Zhao and his colleagues report on their new DNA assembler method in Nucleic Acids Research. Needing only simple DNA preparation and a one-step yeast transformation, this in vivo process can assemble an entire biochemical pathway of Saccharomyces cerevisiae in a single step by taking advantage of homologous recombination. "Assembling genes into a biochemical pathway using a DNA assembler is similar to building a toy train.

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The UK and the European Union have come to a sticking point in the negotiation of how the UK might remain involved in the Horizon Europe research program, the Guardian reports.

The New York Times reports that experts pushed during a meeting of an FDA advisory board for the agency to require more safety data from SARS-CoV-2 vaccine trials.

The Washington Post reports Moderna expects that it will have enough data on its candidate SARS-CoV-2 vaccine to submit to regulatory authorities by mid-November.

In Science this week: ANXA11 variants affect calcium homeostasis and stress granule disassembly in ALS, and more.