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Not Your Typical Registry

In Public Health Genomics, researchers from Johns Hopkins University's Genetics and Public Policy Center propose a blueprint for a national genetic test registry. They say that the registry should be mandatory and that it should contain information so that the analytic validity, clinical validity, and clinical utility may be assessed. "Establishing a registry is a critical first step in the development of a more transparent, quality-centered system of oversight that will better inform and protect the public," they write in the abstract.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.