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Like Siblings, Duplicate Genes Watch Out For Each Other

A recently published paper in PLoS Genetics shows evidence for gene duplication being evolutionarily conserved because it contributes to genetic robustness. Researchers at Duke's Institute for Genome Sciences and Policy looked at a pair of duplicated histone deacetylases, Hst1p and Sir2p, in Saccharomyces cerevisiae. They showed that before duplication, the ancestral protein had functions of both genes, but after, the genes produced two functionally distinct proteins. Despite this, Sir2p can substitute for Hst1p in its absence.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.