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Shutdown Spreading

As the US federal government shutdown drags on, more parts of the government are affected as funding dwindles. The national laboratories, which are run by subcontractors, are now preparing to close as their Department of Energy funding runs out, the Nature News Blog reports.

Los Alamos and Sandia are to close within the next two weeks — on the 18th and 21st, respectively — while Argonne National Laboratory may stay open through the end of the month. In addition, Pacific Northwest National Laboratory and Oak Ridge National Laboratory will likely remain open through November, according to the Nature News Blog.

The Scan

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.

Australian Survey Points to Public Support for Genetic Risk Disclosure in Relatives of At-Risk Individuals

A survey in the European Journal of Human Genetics suggests most adult Australians are in favor of finding out if a relative tests positive for a medically actionable genetic variant.