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Should Indels Get Special Treatment?

Mike the Mad Biologist reaches out for help analyzing indel data. He's using Illumina to generate lists of SNPs for many different bacterial strains, but has found that anywhere from ten to forty percent of the SNPs are indels. His question for fellow researchers is, should he use a statistical analysis program that treats the indels as single characters or not? "I would note that as it gets really cheap to scan entire microbial genomes for SNPs, this will be a problem we have to grapple with," he says.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.