Making siRNAs "gene-like" increases their stability, French biologists report in this week's Proceeding of the National Academy of Sciences. The researchers added short, complementary A5–8/T5–8 3' overhangs to siRNAs, creating sticky overhangs, and called the product ssiRNAs. The added stability upped their RNase protection and in vitro gene silencing by 10-fold.

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.