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Short and Sticky Does the Trick

Making siRNAs "gene-like" increases their stability, French biologists report in this week's Proceeding of the National Academy of Sciences. The researchers added short, complementary A5–8/T5–8 3' overhangs to siRNAs, creating sticky overhangs, and called the product ssiRNAs. The added stability upped their RNase protection and in vitro gene silencing by 10-fold.

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.