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Making siRNAs "gene-like" increases their stability, French biologists report in this week's Proceeding of the National Academy of Sciences. The researchers added short, complementary A5–8/T5–8 3' overhangs to siRNAs, creating sticky overhangs, and called the product ssiRNAs. The added stability upped their RNase protection and in vitro gene silencing by 10-fold.

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Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.

An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.

Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.

In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.