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Making siRNAs "gene-like" increases their stability, French biologists report in this week's Proceeding of the National Academy of Sciences. The researchers added short, complementary A5–8/T5–8 3' overhangs to siRNAs, creating sticky overhangs, and called the product ssiRNAs. The added stability upped their RNase protection and in vitro gene silencing by 10-fold.

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SARS-CoV-2 vaccine developers are evaluating further vaccine doses as well as modified doses to keep up with new viral variants, according to CNN.

The New York Times reports that a new viral variant of concern has been identified in New York City.

In Nature this week: spatiotemporally resolved map of the human cell cycle, folding single-cell RNA sequencing into cancer drug studies, and more.

CNN reports that a US Food and Drug Administration document says Johnson & Johnson's SARS-CoV-2 vaccine meets the requirements to receive an Emergency Use Authorization.