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Sheesh, Now You Want to Know How It Works, Too?

Pharmacogenomics is changing how drugs will have to be evaluated, says Russ Altman at his Building Confidence blog. On the plus side, he writes, we have a better understanding of the biology involved since PGx is based on comprehensive studies of genomics. But our lack of clarity on most compounds' mechanism of action is still a hindrance. "There needs to be an investment in drug mechanism," he writes. "It will make the pharmacogenetic task easier, but will also lead to a more profound understanding of how drugs work and how new drugs may work better."


The Scan

Not Yet a Permanent One

NPR says the lack of a permanent Food and Drug Administration commissioner has "flummoxed" public health officials.

Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.