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"Sharon! … #$%& … Sharon!"

The venerable, if satirical, news organization The Onion reports on some of the discoveries made so far from the study of heavy metal singer and reality TV star Ozzy Osbourne's genome. Ozzy's genome contains "mumbly code that are almost completely indecipherable" as well as "a close genetic link with no other living creature." In addition the singer has the "Sharon marker," The Onion says, and that means he is "predisposed to shuffle about shouting 'Sharon!' The fact that subject is married to a person of this name is a statistically improbable coincidence."

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.