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Sequencing vs. the CT Scan

The Wall Street Journal reports on research out of the Johns Hopkins University Kimmel Cancer Center that describes a new blood test which can decipher a patient’s genetic fingerprint in search of known DNA biomarkers for cancer based on the sequences of several tumor types. According to the WSJ, the researchers said that the cost of their DNA test ― currently about $5,000 ― would soon by comparable to that of a CT scan ― approximately $1,500 ― and that it could be ready for use within two years.

The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.