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Sequencing for Curiosity's Sake

In response to recent suppositions reverberating in the blogosphere, Keith Robison at Omics! Omics! says that "plenty of genomes are still fair game for sequencing." In contemplating what makes a genome "interesting," Robison says that its history, evolution and development, and biochemical makeup come to mind. Overall, the blogger says that while he understands that "it is easy for those of us in the biology community to see the longer threads connecting these projects to human health, or just the importance of pursuing curiosity, but that doesn't always sell well in public," he still finds "it odd that some [biologists] don't see the import and utility of sequencing many, many humans and a lot of vertebrates also. He adds, "Personally, I can't stroll a country fair without wanting to sequence just about everything I see on display."

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.