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Seeing the Rearrangements

In Genome Research, Baylor College of Medicine researchers made a sequence-level chromosomal map of the MCF-7 breast cancer cell line to study its chromosomal rearrangements. Using end-sequence profiling and massively parallel sequencing, they analyzed the chromosomal breakpoints and rearrangements. They identified 79 genes involved in these events, some of which appear to be tumor-suppressor genes or genome stability genes, including BRIP1 and RAD51C. The New York Times reprinted the visualization of the rearrangements here.

 

The Scan

Could Cost Billions

NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars.

Not Quite Sent

The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post.

DTC Regulation Proposals

A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports.

PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy

In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.