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Searching the Transcriptome

Researchers from the J. Craig Venter Institute and the Ludwig Cancer Institute identified genomic rearrangements in a breast cancer cell line using high-throughput transcriptome sequencing. They used 454 Life Sciences sequencing to identify those rearrangements. The gene fusions and truncations they noted included ones that affected the MRE11 and NSD1 genes, which are already known to be involved in oncogenesis. Their work appears in the current issue of PNAS.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.