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Elaine Mardis and her colleagues at Washington University in St. Louis sequenced the genome of a man with acute myeloid leukemia using Illumina's Genome Analyzer II and identified 64 mutations, according the report in the New England Journal of Medicine. Of those, 12 were somatic mutations in coding regions and 52 were somatic point mutations in conserved or regulatory regions.

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Bloomberg reports AstraZeneca may conduct another study of its candidate SARS-CoV-2 vaccine after dosing error.

Moderna is applying for an Emergency Use Authorization for its coronavirus vaccine, according to the New York Times.

The National Health Service is to conduct a trial of Grail's blood-based screening test for cancer.

In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.