Yahoo's new Build Your Own Search Service allows programmers to use Yahoo's index of the web, reports MIT's Technology Review. This service should remove "the biggest barrier to search innovation," according to the article. The head of Yahoo Research says that BOSS projects might come up with better ways to search videos or images, incorporated social networking, or actually understand Web page content rather than the keywords and links.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.