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Scores and Output

At the NIGMS Feedback Loop, Jeremy Berg shares his analysis of whether peer review scores predict scientific output, and he finds that they do. Berg looked at 789 R01 grants that NIGMS funded during fiscal year 2006, linked those grants to 6,554 publications from fiscal years 2007 through 2010, and noted that those publications had been cited 79,295 times, as of this April. Berg then breaks the data down by type of citation (research, review, citation in a highly cited publication, and more), and correlates some of the metrics to percentile score. "Of these metrics, overall citations show the most statistically significant Gini coefficient, whereas highly cited publications show one of the least significant Gini coefficients." Berg writes.

The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.