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Scientists in Swimwear? It Must Be Time for PSB

If you're not in Hawaii just now, you can warm up vicariously with Cameron Neylon's running commentary on proceedings of the open science workshop at the PSB meeting. One of the themes of the session was "the need for persistent identity tokens to track people's contributions, and a need to re-think how citation works, and what citations are used for," Neylon writes. But the main take-home message, he notes, is the need for solid evidence that practicing open science is beneficial:

"We have little if any quantitative information on the benefits of open practice. ... More research and more aggregation of examples will help here but there is a desperate need for numbers and details to help funders, policy [makers], and researchers themselves to make informed choices about what approaches are worth adopting, and which are not."

If you want to check out the rest of what's going on at PSB, there's a running commentary on Friendfeed.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.