"The Big Bang Theory," a CBS comedy about two nerdy physicists, has annoyed some scientists who are bothered by the stereotype of the scientist-as-geeky-loser, according to the New York Times' Dennis Overbye. Though the series is "funny and scientifically accurate" scientists are "put off" by it, he says. But other researchers are lining up to be guests on the show, including Nobel laureate George Smoot, NPR Science Friday host Ira Flatow, and Harvard particle theorist Lisa Randall.