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Scanning PLoS Genetics

The month is at a close, but there are still a few hours left to enjoy the current issue of PLoS Genetics. We gloss a few of the most relevant papers:

In a submission from lead author Sergey Nikolaev at the University of Geneva, a group of scientists discuss the use of ENCODE sequence data to inform our understanding of mammalian history. The work involved "phylogenetic reconstructions based on an unprecedented amount of coding sequences taken from 218 genes," according to the abstract.

Another paper tackles comparative genomics of mitochondria. Lead author Ana Signorovitch from Yale and her colleagues studied placozoan mitochondrial genomes to determine their similarity.

Finally, a team headed up by Washington University demonstrated a new technique using comparative genomic hybridization to characterize copy number variations in 21 mouse strains. "This technique increased the resolution of CNV detection by more than an order of magnitude over previous methodologies," according to lead author Timothy Graubert in the abstract.


The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.