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Scanning PLoS Genetics

The month is at a close, but there are still a few hours left to enjoy the current issue of PLoS Genetics. We gloss a few of the most relevant papers:

In a submission from lead author Sergey Nikolaev at the University of Geneva, a group of scientists discuss the use of ENCODE sequence data to inform our understanding of mammalian history. The work involved "phylogenetic reconstructions based on an unprecedented amount of coding sequences taken from 218 genes," according to the abstract.

Another paper tackles comparative genomics of mitochondria. Lead author Ana Signorovitch from Yale and her colleagues studied placozoan mitochondrial genomes to determine their similarity.

Finally, a team headed up by Washington University demonstrated a new technique using comparative genomic hybridization to characterize copy number variations in 21 mouse strains. "This technique increased the resolution of CNV detection by more than an order of magnitude over previous methodologies," according to lead author Timothy Graubert in the abstract.


The Scan

Missed Early Cases

A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports.

Limited Journal Editor Diversity

A survey finds low diversity among scientific and medical journal editors, according to The Scientist.

How Much of a Threat?

Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned.

PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs

In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.