Researchers at National Taiwan University and the University of Chicago have used whole genome analysis to examine how cis, trans and cis-by-trans elements affect gene expression at different levels of evolution. Publishing in PNAS, they used two behavioral races of Drosophila melanogaster, analyzing the full set of chromosome-substitution lines. They found that few genes are regulated solely by one or the other, and that 80 percent of the differences in gene expression are controlled by at least two chromosomes.
Saying It's Hard to Put Your Finger On Would Be an Understatement
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