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Say What?

At A Quantum Diaries Survivor, Tommaso Dorigo points out a table from a Physics Today article that compares terms that mean something different to scientists than they do to the public. The list includes scheme ("devious plot" versus "systematic plan"), theory ("hunch, speculation" versus "scientific understanding"), and manipulation ("illicit tampering" versus "scientific data processing"), among others. The Southern Fried Scientist has posted a table that his writing class came up, and that includes E. coli ("tainted food" versus "laboratory culture"), mutant ("X-men, abnormal" versus "change in gene"), and significant ("meaningful" versus "statistically supported").

The Scan

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.

Rett Syndrome Mouse Model Study Points to RNA Editing Possibilities

Investigators targeted MECP2 in mutant mouse models of Rett syndrome, showing in PNAS that they could restore its expression and dial down symptoms.

Investigators Find Shared, Distinct Genetic Contributors to Childhood Hodgkin Lymphoma

An association study in JAMA Network Open uncovers risk variants within and beyond the human leukocyte antigen locus.

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.