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Requiring conventional sample size calculations might be an impediment to completing translational or early clinical studies, write Peter Bacchetti and his colleagues at the University of California, San Francisco, in a Perspectives article in Science Translational Medicine. "There is little theoretical or empirical support for the conventional requirement that every study must have at least 80% power," the authors write.

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Nature News reports on the US National Science Foundation's investigations of undisclosed foreign ties among researchers it funds.

Researchers have developed a set of 10 principles to guide how a list of all species on earth should be put together, the Guardian reports.

Wired reports on a new firm developing a gene writing approach for therapeutic genome changes.

In Nature this week: a method called cis-X combines whole-genome and transcriptome sequencing data to identify regulatory noncoding variants, and more.