Samuel Karlin, an emeritus professor of mathematics at Stanford University, died at age 83. Karlin was interested in bioinformatics and mathematical biology and helped early genome sequencing efforts. When Jonathan Eisen was at Stanford, Karlin was one of his mentors.
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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.
A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.
The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."
In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.