Researchers at the Nevada Cancer Institute in Las Vegas found that Sall4, a zinc-finger transcription factor that is expressed very early in embryonic development with Oct4 and Nanog, plays a diverse role in regulating stem cell pluripotency during early embryonic development. Using chIP-chip analysis to map genome-wide gene targets of Sall4 in mouse ES cells, they found that the protein bound 3,223 genes, many of which have major functions in developmental and regulatory pathways.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more