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Safety, Unlike Beauty, Is Not In the Eye of the Beholder

Derek Lowe comments on the news that Pfizer's (now discontinued) inhaled insulin (Exubera) had led to an increased chance of lung cancer in clinical trials. Considering the difficulties and risks of drug development, it's hard to guarantee outcome of clinical trials, especially when they should take into account that disease often happens on the order of years, not months. "The truth, as far as I can see, is that no one can guarantee the safety of a new drug. If you want to take that further, guaranteeing the safety of an existing drug isn't possible, either," he says, at his blog In the Pipeline.

The Scan

Gone, But Now Reconstructed SARS-CoV-2 Genomes

In a preprint, a researcher describes his recovery of viral sequences that had been removed from a common database.

Rare Heart Inflammation Warning

The Food and Drug Administration is adding a warning about links between a rare inflammatory heart condition and two SARS-CoV-2 vaccines, Reuters reports.

Sandwich Sampling

The New York Times sent tuna sandwiches for PCR analysis.

Nature Papers Describe Gut Viruses, New Format for Storing Quantitative Genomic Data, More

In Nature this week: catalog of DNA viruses of the human gut microbiome, new dense depth data dump format to store quantitative genomic data, and more.