Researchers led by Fred Hutchinson's Sam Hanash have published a mouse plasma peptide atlas in Genome Biology. In it, they've identified 13,779 distinct peptides corresponding to about 3,000 proteins that are estimated to span a 7-logarithmic range of abundance in plasma. They say a major finding from this work is novel isoforms and transcript variants not previously predicted from genome analysis, and hope to use the atlas for disease research.
The Rugged Terrain of Mouse Plasma
Jun 04, 2008