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The Rugged Terrain of Mouse Plasma

Researchers led by Fred Hutchinson's Sam Hanash have published a mouse plasma peptide atlas in Genome Biology. In it, they've identified 13,779 distinct peptides corresponding to about 3,000 proteins that are estimated to span a 7-logarithmic range of abundance in plasma. They say a major finding from this work is novel isoforms and transcript variants not previously predicted from genome analysis, and hope to use the atlas for disease research.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.