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A Proposal

Ron Paul (R-Tx.) released a new proposal to cut federal spending for research in a budget plan he says he will enact if elected president of the US in 2012, reports ScienceInsider's Jeffrey Mervis. The proposal "would wipe out large chunks of the government's research portfolio," Mervis says, erasing such programs as the Energy Department's $5 billion Office of Science, the $4.5 billion National Oceanic and Atmospheric Administration, and the US Geological Survey, among others. "Paul would also end funding for all research programs at the US Department of Agriculture, although the department itself would be preserved at its current budget. And he would pare roughly $7 billion from the current $30 billion budget for the National Institutes of Health," Mervis adds. The plan says nothing about the National Science Foundation.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.