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RNAi and Huntington's Disease

Alnylam and Medtronic are working together to develop RNA interference as a treatment for Huntington's disease, reports The Wall Street Journal. Medtronic is working the task of creating a pump and catheter system to deliver Alnylam's therapy to the right spot of the brain "without hiking up cranial pressure too much and damaging brain tissue," the Journal adds. Alnylam is using an siRNA to block mRNA. "What we do is shut off the spigot," Alnylam president Barry Greene says. "We stop the creation of a protein."

The Scan

Billions for Antivirals

The US is putting $3.2 billion toward a program to develop antivirals to treat COVID-19 in its early stages, the Wall Street Journal reports.

NFT of the Web

Tim Berners-Lee, who developed the World Wide Web, is auctioning its original source code as a non-fungible token, Reuters reports.

23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.