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Richard Darwin Keynes Dies

Richard Darwin Keynes, a great-grandson of Charles Darwin and a nephew of John Maynard Keynes, died in June. He was 90. An obituary in the UK's Guardian notes that Keynes "rose to eminence in his own right in the field of physiology." He studied the electrical conduction of signals along nerves, showing that the impulse was associated with the movement of sodium ions and potassium ions, and determined how electrical eels are electric. Keynes also wrote a number of books about Darwin. "[He] made a significant contribution to our understanding and appreciation of Darwin's genius," writes Julian Fitter in the Guardian.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.