Embryonic stem cell researchers are weighing their career options and dealing with the worry that they may not be able to continue their work, says the New York Times' Amy Harmon. In August, federal judge Royce Lambeth ruled that federal money could not be used to fund embryonic stem cell research. The researchers, who have been operating with federal funding for the past year, may see their money dry up completely if an appeals court doesn’t overturn Lambeth's ruling.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.