In a study in the American Journal of Human Genetics, researchers at the University of Edinburgh say they've discovered three genes that make a substantial contribution to blood-clotting times. The team, led by Ian Deary, says identifying the genes could further scientists' understanding of deep vein thrombosis, heart attacks, and some types of stroke. The study looked for associations between 500,000 genetic markers and clotting time, measured by activated partial thromboplastin time. Three genes — F12, HRG, and KNG1 — seemed to be responsible for a substantial amount of the variation in clotting speed among healthy individuals. Deary says the researchers are planning to follow up on the findings to establish their clinical significance.
Researchers Discover Three Genes Linked to Clotting
Mar 23, 2010