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Reprogramming Prize

For their work on reprogramming cells, John Gurdon at Cambridge University in the UK and Shinya Yamanaka from Japan's Kyoto University have won the Nobel Prize in Physiology or Medicine, Reuters reports. "The Nobel Prize recognizes two scientists who discovered that mature, specialised cells can be reprogrammed to become immature cells capable of developing into all tissues of the body," The Nobel committee says in a press release. "Their findings have revolutionised our understanding of how cells and organisms develop." Gurdon and Yamanaka will share the $1.2 million prize.

In the early 1960s, Gurdon was the first person to clone an animal, The Guardian reports. Gurdon transplanted a nucleus from an adult frog's intestine cell into a frog egg, which then developed into a healthy tadpole. Then, in 2006, Yamanaka reported on his work reprogramming mature mouse cells into induced pluripotent stem cells. "By drawing on the methods developed by Gurdon and Yamanaka, scientists can create cells that carry specific diseases and watch how they grow. The procedure could shed light on the biological mechanisms that go awry in disease and reveal new ways to treat them," The Guardian adds.

Nobel week continues with more prizewinners being announced each day. For the gambling types, bookmakers are taking bets.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.