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In Real-time, Though Not in Living Color

By using single-gene integrations with green fluorescent protein, Yaron Shav-Tal and his colleagues at Bar-Ilan University were able to visualize a single gene undergoing transcription in vivo in mammalian cells, they report in Nature Methods. "In our system, the cell line has a target sequence in its genome and any sequence you send in will always go to that place," Shav-Tal tells Nature. "You can make different cell lines and not be worried about where the gene went in."

On its blog and on YouTube, The Scientist posted videos that the researchers made. This one is of a continuously transcribing single cyclin D1 gene:

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.