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But the Real Question Is, Were There Originally Fifteen?

If you've been in need of a good protein-related laugh, Blogger Bosco at Trapped in the USA delivers. Don't miss his entertaining list of the Ten Commandments of Protein Folding. Some samples:

  • Thou shalt have no other structure before the one true native structure.
  • Thou shalt not make unto thee any false structure of the native state, or any likeness of any structure such as predicted by molecular dynamics or homology modeling programs.
  • Thou shalt not covet thy neighbor's structure, as designated by SCOP or CATH, nor his sequence, nor his function, for thy structure has been given thee by thy sequence alone.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.