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The R&D Crystal Ball

A funding forecast put together by Battelle and R&D Magazine foresees global R&D spending in the life sciences increasing from $181.6 billion in 2012 to $189.3 billion in 2013, and an increase from $81.5 billion to 82.7 billion for the US.

"The estimates and forecast show that US industry should turn the corner and begin increasing their R&D investment in 2013," the report says. "The global industry, while affected by a slowdown from 2009 to 2012 is on a stronger R&D growth trajectory into 2013."

Battelle and R&D Magazine also surveyed about 275 members of the R&D community, MedCity News adds, and the respondents were optimistic about 2013, with more than half of the respondents saying they expected their R&D budgets to increase this year as compared to last.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.